Oddly enough, there was someone in my Anime club with a Husky (affectionately named after Kiba from Wolf's Rain) who was part wolf. How much wolf is in him, I don't remember. Might be half, might be not. In Kiba's case, he was either really well trained, bred from a docile wolf, or both.

I've got my eyes open for mixed breeds too! Amanda is half-Bichon, half-Maltese, and she lived to be 16. :3